When applying the Striker's unique Bowling ball launcher onto the Big Boy it will actually result in one 'gaining' modified bowling balls, as each ball can be retrieved individually.

Due to the way that the legendary Two Shot prefix is programmed, the MIRV nukes will have a much larger blast radius and damage, comparable to 12 individual mini nukes.

If they fly a certain distance they will disperse into 12 bomblets.

The Big Boy with the MIRV mod will shoot 12 mini-nukes due to both of the mini-nukes fired each splitting into 6.

The Big Boy can be bought from Arturo Rodriguez in the Diamond City market.

Nuka-nuke launcher, a unique version that deals 50% more damage than the standard model by firing quantum-enhanced Nuka-nukes.

The Striker, a unique version that fires modified bowling balls instead of mini nukes.

It is also compatible with the unique Nuka-nuke launcher's unique modification, meaning that one can effectively do double the damage of a regular Fat Man, and 50% more than the regular Big Boy, the only downside is having to actually craft the Nuka-nuke ammo for it. In addition, the cost of this weapon is high, at around 14,000+ caps with no Charisma and related perks or effects, making it one of the most expensive weapons in the base game. The blast radius of this weapon's mini nukes is substantially larger than normal and that the nukes lose their momentum and fall to the ground after splitting. The Big Boy will shoot twelve mini nukes, while only consuming one. The Big Boy is compatible with the MIRV launcher mod.

The Big Boy is a Legendary Fat Man with the Two-Shot effect, allowing it to shoot two mini nukes at once for the cost of only one, giving it the most damage potential from a single shot in the entire game, with the sole exception of the nuke, which is obtainable only through console commands.

Big fallout 4 mods